A Life
in Motion
A Life
in Motion
50%
Of people with knee osteoarthritis will have a total knee replacement done during their lifetime.
A Life
in Motion
50%
Of people with knee osteoarthritis will have a total knee replacement done during their lifetime.
The Need for Innovation in Tissue Regeneration
OA is a growing affection
OA has NO CURE
OA limits life and
increases mortality
No approved-drugs
slow progression
OA is a growing affection
OA has NO CURE
OA limits life and
increases mortality
No approved-drugs
slow progression
OA is a growing affection
OA has NO CURE
OA limits life and
increases mortality
No approved-drugs
slow progression
OA is a growing affection
OA has NO CURE
OA limits life and
increases mortality
No approved-drugs
slow progression
OA is a growing affection
OA has NO CURE
OA limits life and
increases mortality
No approved-drugs
slow progression
OA is a growing affection
OA has NO CURE
OA limits life and
increases mortality
No approved-drugs
slow progression
OA is a growing affection
OA has NO CURE
OA limits life and
increases mortality
No approved-drugs
slow progression
OA is a growing affection
OA has NO CURE
OA limits life and
increases mortality
No approved-drugs
slow progression
The Need for Innovation
in Tissue Regeneration
OA is a growing affection
OA has NO CURE
OA limits life and
increases mortality
No approved-drugs
slow progression
THE PROBLEM
Osteoarthritis
Is a debilitating condition that affects 500 million people and has no cure. Traditional treatments offer limited relief and often require invasive procedures.
By 2040 will affect 1.9 billion people worldwide.
OUR SOLUTION
A local injection to stimulate tissue regeneration
MicroRNAs are very small molecules that circulate in our body fluids. They can regulate cells to improve their function.
Our modified miRNAs promotes cell restoration inducing long-term tissue regeneration.
Lipid Nanoparticles
Lipid Nanoparticles
OUR SOLUTION
A local injection to stimulate tissue regeneration
MicroRNAs are very small molecules that circulate in our body fluids. They can regulate cells to improve their function.
Our modified miRNAs promotes cell restoration inducing long-term tissue regeneration.
THE PROBLEM
Osteoarthritis
Is a debilitating condition that affects 500 million people and has no cure. Traditional treatments offer limited relief and often require invasive procedures.
By 2040 will affect 1.9 billion people worldwide.
OUR SOLUTION
A local injection to stimulate tissue regeneration
MicroRNAs are very small molecules that circulate in our body fluids. They can regulate cells to improve their function.
Our modified miRNAs promotes cell restoration inducing long-term tissue regeneration.
THE PROBLEM
Osteoarthritis
Is a debilitating condition that affects 500 million people and has no cure. Traditional treatments offer limited relief and often require invasive procedures.
By 2040 will affect 1.9 billion people worldwide.
Lipid Nanoparticles
Tissue Regeneration and Cell Function Restoration
Tissue Regeneration and Cell Function Restoration
Our miRNA therapy offers a non-invasive solution that addresses the root cause of osteoarthritis, promoting regeneration and healing
MicroRNAs are small, non-coding RNA molecules that regulate gene expression and have a big impact on many biological processes
Change
Microenvironment
With a specific combination of MicroRNAs we can modify the cellular environment in the joints
Regulation
of Cell function
We reprogram diseased cell´s function to restore cartilage production
Tissue
Regeneration
A solution containing MicroRNAs is locally injected into the lesion site to stimulate tissue regeneration
MicroRNAs are small, non-coding RNA molecules that regulate gene expression and have a big impact on many biological processes
MicroRNAs are small, non-coding RNA molecules that regulate gene expression and have a big impact on many biological processes
Change
Microenvironment
With a specific combination of MicroRNAs we can modify the cellular environment in the joints
Change
Microenvironment
With a specific combination of MicroRNAs we can modify the cellular environment in the joints
Tissue
Regeneration
A solution containing MicroRNAs is locally injected into the lesion site to stimulate tissue regeneration
Tissue
Regeneration
A solution containing MicroRNAs is locally injected into the lesion site to stimulate tissue regeneration
Regulation
of Cell function
We reprogram diseased cell´s function to restore cartilage production
Regulation
of Cell function
We reprogram diseased cell´s function to restore cartilage production
MicroRNAs are small, non-coding RNA molecules that regulate gene expression and have a big impact on many biological processes
MicroRNAs are small, non-coding RNA molecules that regulate gene expression and have a big impact on many biological processes
Change
Microenvironment
With a specific combination of MicroRNAs we can modify the cellular environment in the joints
Change
Microenvironment
With a specific combination of MicroRNAs we can modify the cellular environment in the joints
Tissue
Regeneration
A solution containing MicroRNAs is locally injected into the lesion site to stimulate tissue regeneration
Tissue
Regeneration
A solution containing MicroRNAs is locally injected into the lesion site to stimulate tissue regeneration
Regulation
of Cell function
We reprogram diseased cell´s function to restore cartilage production
Regulation
of Cell function
We reprogram diseased cell´s function to restore cartilage production
Tissue
regeneration
Cellular
restoration
Innovative
formulation
MicroRNA
MicroRNA
Tissue
regeneration
Cellular
restoration
Innovative
formulation
MicroRNA
MicroRNA
Tissue
regeneration
Cellular
restoration
Innovative
formulation
MicroRNA
MicroRNA
Our proprietary combination of modified MicroRNAs stimulate the revitalization of chondrocytes
Innovative delivery system ensures microRNAs releasing precisely when and where they are needed
The restoration of articular cells sparks a cascade of cartilage production, leading to a profound reduction in pain and inflammation
Meet the Dharma Team
The Minds Behind the Innovation
Management
Lab Team
Advisors
Gaston Topol
Co-Founder
Chief Medical Officer
Franco Cescotti
Co-Founder
Chief Executive Officer
Diego Croci
Co-Founder
Chief Scientific Officer
Andrés Graziosi
Chairman of Board
Chairman of Board
The Minds Behind the Innovation
Management
Lab Team
Advisors
Gaston Topol
Co-Founder
Chief Medical Officer
Franco Cescotti
Co-Founder
Chief Executive Officer
Diego Croci
Co-Founder
Chief Scientific Officer
Andrés Graziosi
Chairman of Board
Chairman of Board
The Minds Behind the Innovation
Management
Lab Team
Advisors
Gaston Topol
Co-Founder
Chief Medical Officer
Franco Cescotti
Co-Founder
Chief Executive Officer
Diego Croci
Co-Founder
Chief Scientific Officer
Andrés Graziosi
Chairman of Board
Chairman of Board
